娌℃浜灏变寰椋╋

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涔涓锛杩浜杩稿璋辩锛xx椋╀腑xx绱锛瀹楠琛ㄦxx绱浠ユ姝荤缁锛姝ゅxx椋╁浠ラ茬

ｄ浠ョ杩浜XX绱茬浣澶灏借揪伴茬锛

浜澶ф璋绱

ㄥ涔锛浠娴浼骞跨ｄ椋╀腑绱芥锛

绾㈢

涔椋╁涓借但跺ㄥ锛灏辨跺绾㈢

缃浼锛杩浜骞存ョ姐寰峰界瀛锛跺涓绾㈢茬锛瑰插虹锛涓杩娌荤虹

遍绱

浠骞达榛告瑰抽氨ㄤ榛告涓澶ч遍绱

缃浼锛遍绱灏辨互寮哄ぇ姘уц绉扮缁姘у浼や澶㈡х剧崇郴锛濡蹇琛绠＄剧琛拌杩灏辨负浠涔锛遍绱藉惰跨ょ澧夸澶扮瀛绌朵璇杩癸遍绱瀵逛澶瑰荤缁剧浜寮哄ぇ朵ㄣ

胯剁

缁胯朵ュ荤浜轰汉界ラ锛朵腑胯剁涓娌°

缃浼锛煎扮瀛锛灏胯剁杈崇跨らㄤ锛瓒杩涓跨や绉澶便灏朵ㄥ涔寰讹绌堕瀵间汉琛ㄧず锛杩椤圭榧浜哄锛

借

杩涓ぇ瀹跺芥杈锛浣绾㈤淇ヨ浜澶у搴璇ラ藉э杩朵腑璧峰抽ㄧ锛灏辨借

缃浼锛绌惰〃借ㄥ棰缁绛舵ц跨ょ娌荤棰叉归㈤芥绉浣ㄣ借跨やㄤ富瑕浣ㄦ剁缁澧娈淇杩浜°璋杞Щ渚佃归

濮榛绱

濮涔绁朵腑濮榛绱冲抽瑕

缃浼锛缇界瀛拌绌舵剧ず锛卞卞楂搴绾濮榛绱锛璋瀛跨よ浆绉诲瀛垮瀛芥躲界板涓剁癸杞跨よ绋╃ㄥ榛绱藉澶╃堕跺╃绐达澶уぇ浣跺╂不璐圭ㄣ

杩浜芥

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绗绉锛灏浜轰缁烘ワ娴告鼎ㄩ娴搴绉绱婧舵恫涓缁缉╂ｃ

绗绉锛浠ュぇ榧涓哄楠瀵硅薄锛瀵瑰堕娉ㄦ娉ㄥ绉绱锛瑙瀵板剁缁╂ｃ

瀵逛涓绉瀹楠瑰浠苟娌℃存涓烘浠杩涓瑗挎ヨ寰杩浜绱锛娉瀹缁娴告鼎ㄥ舵憾娑蹭腑

绗绉瀹楠瑰缁纭璁╀汉杩浜椋╂舵锛

浣寰涓锛

缁澶ч娉ㄦ婊存敞绱锛芥楂搴绾浜哄涓锛杩浜ュ荤椋╋冲版瑕浣涓涓澶х

姣ぉ1ㄨタ绾㈡

2011骞达宸澶у娆ф＄瀛浜涓涓楠锛姣ぉ姣15mg澶ч绾㈢锛╁瑗夸璧绌跺锛缁ㄧ绾㈢锛浠ュ寮哄瑗夸璧瀵瑰虹娌荤

㈢颁汉韬锛60kg绠锛涓浜轰澶╄900mg绾㈢涓よタ绾㈡跨绾㈢负 0.2锝20姣锛涓涓瑗跨孩匡藉告0.05姣绾㈢锛涔灏辨姣ぉ瑕1800よタ绾㈡匡宸澶1靛点

姣ぉ1ら告

瀵姝瑰绔澶у绌惰2003骞村浜涓椤瑰楠锛浠ユぉ姣375-3000 mg灏遍绱╁缁澶ч锛舵ｇ茶姒姣娌℃遍绱澶ч浣75%瀵逛ぇ朵娑锛杩涓哄捐

浠浣姣375mg锛60ょ浜烘ぉ瑕22500mg遍绱榛告涓遍绱负5%锛绠涓ユぉ瑕450g榛告锛涔灏辨1ゃ

杩涔浼间惧般浣浣ラ榛告澶灏变ゅ锛灏1500锛璐ㄩ瑕涓涓浠ラ抽涓涓锛涓璧峰锛

姣ぉ200涓娉¤

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浠灏0.1%绠锛60kg浜烘ぉ瑕60g胯剁缁胯朵腑胯剁害涓15%锛涔灏辨锛浣姣ぉ瑕400g缁胯跺杩涔姒蹇靛涓涓娉¤朵腑跺2g锛涔灏辨浣姣ぉ瑕200涓娉¤剁跺涓场跺瑕ㄩㄥ娌瑰

姣ぉ16700剁孩

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㈢涓涓锛60ょ浜烘ぉ搴璇ユ37500mg借1L绾㈤涓借负1.5-3mg涔灏辨锛浜烘ぉ瑕冲涓12500L绾㈤锛涓剁孩涓750ml锛稿浜汉姣ぉ瑕涓16700剁孩锛

姣ぉ3ょ濮

2008骞村琛ㄥCancer Research蹇涓涓绡绔剧ず锛姣ぉ缁澶ч娉500mg/kg濮榛绱锛杩缁3ㄥ剁灞姣瀵圭х朵40%

濮涓榛绱害涓2%锛㈢涓ワ60kg浜烘ぉ瑕1500g濮锛涔灏辨ゃ瑕よ规涔濂借锛杩ょ濮锛浣寰涓锛

娉ㄦ浠ヤ璁＄涓涓璁惧锛灏辨杩ュ荤藉100%琚告躲浜瀹涓锛椋╃娑杩ヨ娑诧缁婊ゆㄨ韩锛告剁澶фｃ

淇ュ涔卞

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涔充浜椋╁绱绌舵绔芥帮绌跺ㄤ澶瀹楠涓锛灏缂轰复搴璇楠绌躲涔灏辨锛ㄧ╄韩涓浣浜鸿韩涓涓涓瀹ㄣ涓锛稿ㄤ涓‘

浠ㄧ╁楠版涓鸿涓甯涓存婕跨杩绋棣瑕楠璇舵у瀹ㄦэ借FDA瑰ㄤ复搴璇楠锛涔缁冲涓村璇楠锛借瑰涓甯

ラㄥヨ锛涓绉濮榛绱妞╄FDA瑰涓甯锛娌荤翠ㄦ不х锛璺炽朵璋绱锛芥病瑰杩ヤ复搴璇楠澶锛FDA杩惧琛ㄧず锛涓胯绾㈢

浠ワ浠藉扮璋绱锛堕ュュ昏ˉ锛锛涔瀹板ぇ浜浣ㄣ

浠ュ娌℃ㄥ

杩瑕锛WHO虹遍╁绱涓涓ュ悍楗锛姘存ラ锛缇界瀛涔句2012骞村甯瀛娲昏ュ诲杩ㄦ涓猴澶ュ讳赴瀵姘存锛藉棰叉浜瑰绫诲跨ゃ浣楂瀛濂藉

浠ユ浠杩浜濞烘稿锛

骞朵浠宠〃杈剧

棣锛涓妯＄姒蹇碉骞朵浜绉瑰椋╁氨涓瀹涓浼寰锛

绗锛浜椋╁浠ラ浣瑰锛浣苟涓崇瀹浠浠ョㄦユ夸唬╂不锛

绗锛寮浣ㄦヨ锛澶锛姣ヨ冲400姘存锛浠ヨ寰村寰ュ悍剁锛浣涓诲涓轰棰茬辫垂澶ч储ヨ喘涔版璋椋┾锛澶挎澶чㄥ涓椋╀ュ悍楗瑰椹般

浠ュ绉姘存褰舵璇ヨ榧辩锛涓杩蹇浠ヤ负浜浜涓瑗垮氨涓浜澶у浜锛翠瑕杞讳俊XX娌荤浼瑷

Yaxiong Tang锛 Basmina Parmakhtiar锛 Anne R. Simoneau锛 Jun Xie锛 John Fruehauf锛 Michael Lilly and Xiaolin Zi. Lycopene Enhances Docetaxel's Effect in Castration-Resistant Prostate Cancer Associated with Insulin-like Growth Factor I Receptor Levels. Neoplasia Volume 13 Number 2 February 2011 pp. 108-119

Kang SY锛 Seeram NP锛 Nair MG锛 Bourquin LD. Tart cherry anthocyanins inhibit tumor development in Apc(Min) mice and reduce proliferation of human colon cancer cells. Cancer Lett. 2003锛194锛13-19.

Michael J. Weyant锛 Adelaide M. Carothers锛 Andrew J. Dannenberg锛 and Monica M. Bertagnolli. Catechin Inhibits Intestinal Tumor Formation and Suppresses Focal Adhesion Kinase Activation in the Min/+ Mouse. Cancer Res January 1锛 2001 61锛 118

Harper CE1锛 Patel BB锛 Wang J锛 Arabshahi A锛 Eltoum IA锛 Lamartiniere CA. Resveratrol suppresses prostate cancer progression in transgenic mice锛 Oxford Journals Medicine & Health & Science & Mathematics Carcinogenesis Volume 28锛 Issue 9Pp. 1946-1953.

Vesna Milacic锛 Sanjeev Banerjee锛 Kristin R. Landis-Piwowar锛 Fazlul H. Sarkar锛 Adhip P.N. Majumdar锛 and Q. Ping Dou. Curcumin inhibits the proteasome activity in human colon cancer cells in vitro and in vivo. Cancer Res. 2008 September 15锛 68(18)锛 7283-7292. doi锛10.1158/0008-5472.CAN-07-6246.

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