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ㄥ钩琛＄舵锛辩寰╂ぉ浣匡浜轰辩辨锛濡朵技婕锛灏卞藉诲卞楠ㄧ涓娆″ㄦ．灏瑙扮锛фффэ濂界浠や浜鸿崇尽锛

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浠ュ瀛锛涓复搴荤锛涓㈣浜剧瀛灏辫澶村ぇ锛浠ヤ涓涓灞寮瀹浠缃

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瀛锛绂讳寮寰╁

娉姹缁锛ㄥヤ钩杩浠ｈ阿绗姝ワ琚姝ユ娑插惊杩ュ拌ㄨ瀹撮瑕娑告躲姘у瑙ｃ杞绛杩绋锛借川娣绮缁寸绱绛浠ｈ阿涔绫讳技杩绋

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姝ｅ父典锛杩涓绋浼寰绋冲璋锛榛濂锛浣澶灏娣绮锛烘芥弧瓒虫甯哥姹

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璁╂浠ョ寰╁浠ュ芥ㄥ缁缁浼绱ч澧ヨ板绱遍╋

绾镐滑拌寰╁浜涔锛界惰寮鹃澶ц缁缁缁涓虹锛浣杩浜缁缁璁╀璧锋ョ锛婧澶村藉氨井╁浠ｈ阿烘ョ瀛

缁虹涓璇翠锛冲璇绮寰╁锛寰藉氨瀛姝ｇ姝诲杩锛ヨ锛ヨ磋ョ瀛舵у惊锛煎濂藉ソ璀锛

绮撅姝诲

涓浜绌惰〃灏锛瀵硅韩浣ソ澶锛浠ョ澶╂浜涓浜ュ悍楗х锛婚绾㈤剁锛

浣澶ч锛抽挎锛卞灏卞ぇ浜锛

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讹绉瀛涔锛绮惧寸浼や涓缇ょ存稿筹

棣锛绮句杩╁版存цㄨ涓匡╁版存ц戒骇璁稿姣绱锛瀹规寮搴

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姝诲翠锛

姝诲锛繁煎藉瀹濂斤瀹涔瀵硅繁蹇濉扮锛浣缁磋瑕姝昏繁

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杩锛绉瀛浠锛归寰╋浠ョㄦュ府╂不楂琛姘ㄧ杩绉锛杩濂芥涔姝诲濂芥锛

濡浣ユ卞ュ悍楗锛硅娲绘瑰杩浠涔归寰╃娉锛杩涓互浼村虫敞村浜浠澶╁氨涓灞寮璁蹭

1. Tremaroli V, B?ckhed F. Functionalinteractions between the gut microbiota and host metabolism. Nature. 2012 Sep 13;489(7415):242-9.

2. Liu HX, et al. Implications ofmicrobiota and bile acid in liver injury and regeneration. J Hepatol. 2015 Aug 6. pii: S0168-8278(15)00533-4.

3. Szabo G, Petrasek J. Inflammasomeactivation and function in liver disease. Nat Rev Gastroenterol Hepatol. 2015 Jul;12(7):387-400.

4. Henao-Mejia J, et al. In?ammasome-mediateddysbiosis regulates progression of NAFLD and obesity. Nature. 2012 Feb 1;482(7384):179-85.

5. Vajro P, Paolella G, Fasano A. Microbiotaand gut-liver axis: their influences on obesity and obesity-related liverdisease. J Pediatr Gastroenterol Nutr. 2013May;56(5):461-8.

6. Quigley EM, Stanton C, Murphy EF.The gut microbiota and the liver. Pathophysiological and clinical implications.J Hepatol. 2013 May; 58(5):1020-7.

7. B?ckhed F, et al. The gut microbiotaas an environmental factor that regulates fat storage. PNAS 2004; 101:1571815723.

8. Jasmohan SB, et al. TheIntestinal Microbiota and Liver Disease. Am J Gastroenterol Suppl 2012; 1:9 14.

9. Bajzer M, Seeley RJ. Obesityand gut flora. Nature. 2006 Dec21;444(7122):1009-10.

锛绔锛杞璇烽欢绯伙lanch@biomed.tsinghua.edu.cn锛

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