濡濡即瀛╁濂斤

镐俊澶у借藉锛璁烘ㄥ褰辫浣涓杩ㄦ浠ㄥ达跨澧涓己涔辩瀛╁锛绘村涓瀹

ｄ锛姣辩杩浠涔绱褰卞瀛╁杩浜ф煎琛涓虹圭圭

2015骞7锛McMaster澶у绌惰浠ㄣ堕璁蹇涓琛ㄨ锛浠浠ㄥ妯″涓姣浜插ㄥ瀛胯绋涓即锛芥杩褰卞瀛╁寰╃兢缁锛浠杩涓姝ュ奖瀛╁ф煎琛涓虹

护锛you锛浜猴dian锛锛che锛濂锛dan锛

涓杩浠ヤ缁扮涓绌惰浠板э姣绔ｄ澶灏ㄤ虹灏变濡寮浜锛藉ぉ澶╁绌跨藉ぇ瑜搴跺ぇ╀滑冲濡锛肩绉澹锛斤锛锛涓绉榧杈ㄤ璧疯绾夸瑙

绌朵汉瀵瑰浠浜涓浜澶锛寰颁4缁涓灏锛涓轰存板拌绗规跨澧涓锛4缁灏璧蜂瀛锛

1. 瀛ゅ块锛ㄦ澧涓锛ㄦ扮姣榧寮灏锛虫病姣浜查即垮ぇ灏锛

浠浠ヨ涓哄ㄦ澧涓垮ぇ灏涓病寰╃锛浜瀹涓灏杩涓浜瑰寰╃锛涓杩杩涓癸浠ュㄨ涓锛

2. 姝ｅ父榧锛ㄦ澧涓锛辨浜查即垮ぇ灏锛

3. 瀛ゅ块锛ㄩ澧涓锛娌℃姣浜查即垮ぇ灏锛浠ヨ涓哄ㄩ澧涓垮ぇ杩浜灏瀛ㄥ井╋浣涓瀛ㄧ瑰浣锛

4. 姝ｅ父榧锛ㄩ澧涓锛辨浜查即垮ぇ灏

涓ワ杩4缁灏ㄥ澹浠姣涓椹变娇涓锛璧板浜涓榧杞ㄨ抗

瀹楠1锛缂轰扁涓姝ｅ父寰╃兢+涓姝ｅ父琛涓

棣锛绌朵汉杩瀵瑰杩琛浜涓绯诲瀹锛zhe锛楠锛mo锛锛瀛ゅ块涓姝ｅ父榧锛跨涓绉绫荤寰╃兢浣锛骞朵ㄨ涓轰涔捐宸

ㄥ楠涓绘惧村蜂琛ㄧ翠挎涓绉诲ㄥ颁锛翠挎ㄦ浜版瑰锛ㄨ熬撮跨堕村浜规涓ｆ舵

瀹楠2锛缂轰+姝ｅ父寰╃兢涓姝ｅ父琛涓

涔绌朵汉姝ｅ父榧寰╃兢锛Щ妞版瀛ゅ块浠ュ姝ｅ父榧涓ょ灏浣

涓涔浠ュ浠氨颁姣辩界跺ㄤ寮濮浜稿姝ｅ父寰╃兢绉绘锛浣涓ㄤ瀛ゅ块涓姝ｅ父榧浣寰╃兢灏变骇浜捐宸锛骞朵琛ㄧ轰存剧绛躲

瀹楠3锛姣+涓姝ｅ父寰╃兢姝ｅ父琛涓

ｄ濡ㄤ缂轰辩典锛灏瑙颁涓姝ｅ父寰╁杩涔瀹楠浠ラ锛瀛ゅ块姝ｅ父榧浣寰╃兢浣涓风锛涓惧寸涓浜锛浠ヨ涓哄寰╃兢骞朵姝ｅ父

惰锛ㄦ姝ｅ父榧琚涓轰袱缁锛浜涓杩颁袱绉涓寰╃兢绉绘涓ょ姝ｅ父榧寰╃寰镐技锛涔娌℃虹琛涓哄ф间捐宸涔灏辨锛浜茬虫锛璁╁瑙扮涓姝ｅ父寰╃兢寰姝ｅ父浜~

涓㈢瀹楠圭锛娌″崇郴锛绗挎伙kuai锛缁锛shuo锛锛ren锛璇锛hua锛浜锛

娌℃姣浜查即灏锛充娇浜姝ｅ父寰╃Щ妞锛涔藉ㄤ灞轰姝ｅ父寰╃锛浠戒灞轰澶甯哥ф煎琛涓轰

姣浜查即灏锛充娇浜涓姝ｅ父寰╃Щ妞锛寰╃兢缁涔浼ㄤ浜甯革骞朵芥ユ姣杈姝ｅ父ф煎琛涓轰

姣卞氨姝や澶э

绗ㄥ瀹杩浜瀛绔崇濡浜涓佃

璁轰璇璐归杩浠炬《缈诲烘ョ锛胯繁璋㈣濡с

杩娌℃瀛╁濂崇浠浠瀹瑕濂藉ソ繁瀛╁垮~

De Palma, G., etal. Microbiota and host determinants of behavioural phenotype in maternallyseparated mice. Nat Commun. 2015 Jul 28;6:7735.

锛浣锛灏锛澹绌剁锛ユ瑰