娉ㄥ姣姣绱锛涓姝㈢ょ辫涔绠锛

姣姣绱涓村搴

姣姣绱浜虹被ョ寮烘绱涔涓锛浣姣姣绱ㄤ复搴涓村ョ瓒ヨ瑕浣ㄣや娑镐绉辩汗浠ュ锛浣杩ラ姣姣绱浠ョㄦユ不浠涔锛

涓灏ㄤ寮剧浣灞绀轰涓姣姣绱锛淇濡ラ锛ㄣ

ㄧ澶绉锛姣姣绱娉ㄥょ辩虹㈤ㄧ琛ㄦ瑙ｅ濡涓炬绀猴ㄩ㈤ㄥ甯寰澶琛ㄦ姣缁剁缉戒寮璧风瑰琛ㄦ

姣濡锛棰剁缉浼璁╃姣涓朵浼浜х璋ご绾广艰疆剁缉浼瀵艰撮奔灏剧汗姝わ村舰荤浼搴姹缇瑕姹锛灏姣姣绱娉ㄥ扮稿琛ㄦ褰涓锛杩杈惧版ゅㄧ辩汗

姣姣绱ㄥ磋浣绉浼缉姝わ瀵瑰ュぇ姹缇瑷锛浠ラ杩娉ㄥ姣姣绱规浣绉杩杈惧扮哥

充ぇ瀹舵冲姣姣绱娉ㄥょ辨锛灏ラ戒璇翠锛存涓涓ゅ剧с

姣姣绱ㄥ锛

拌锛瑕浣锛灏变瀹椋┿娉ㄥ缇涔涓渚澶歌淇绁ㄤ瀹涓荤娲俱姹缇ㄩ╁井村舰朵瀹瑕灏璋ㄦ板ヨ

搴璇涓澶璇达浠ヨ璋姣姣绱藉芥浜浠涔ㄣ

涓

姣姣绱娉ㄥ涓ㄥ浜哄戒虹澶寸娴风剁琛ㄧ杩浜璞′╁娉ㄥ浼间芥病蹇惰绯伙浠涓娓妤蜂

涓ㄨ╁剧稿崇

变ぇ充姣姣绱瀹ㄦх瀹ｄ锛涓浜姹缇戒炬捐惰浜瀹涓锛姣姣绱涓澶╁锋镐浣ㄣ杩浜╁凹涓纭搁绱澶绮绱姘ㄥ虹绫绘绱绛绛寰澶╅藉藉寮鸿姣姣绱浣浠寰戒骇澶稿锛冲翠涓绛电

澶锛姣姣绱涔骞堕ㄤ浜恒ｆㄥ寸缁浜烘芥敞灏锛杩涓归甯搁瑕杩浜剧Eaton-Lambert缁煎寰缉т晶绱㈢‖绛绛

讹ㄤ浜浜舵ц跨よ灏ｈ涓娉ㄥ姣姣绱涔戒骇澶稿

涓敞灏浣稿崇

肩琛跨芥甯歌ㄣ杩冲澶у涓琛裤娉ㄥ琛垮寰涓烘颁琛绠°姝わ娉ㄥ跺荤寰寰浼ㄦ缁澶淬

惰锛ㄩ㈤灏ゅ舵肩跺ㄥ存甯镐赴瀵绾垫í浜ら灏绠★浠ヨ夸涓涓哄父瑙ㄣ讹变浜ㄤ杞缁杈涓虹撅浠ヨ垮褰卞杩藉ㄥ存╂ｃ

涓╂虹稿崇

涓村涓甯歌浜ㄧ虫敞灏╁ㄥ存╂ｏ褰卞浜涓不崇杩渚垮藉村绉琛ㄦ涓跺绗瀹逛瀵圭О杩荤缁崇郴瀵ㄦ敞灏姣姣绱讹ㄧ澶达ㄧ娉ㄥ娣辨锛虫敞灏堕澶寸瑰藉璁茬┒讹姹缇绋搴冲浜杩濂藉渚濡锛濡娉ㄥ姹缇涓椤惧荤辨╂敞灏哄锛涔藉村风楹荤

涓稿崇

姣姣绱绉寰瓒ｇ┿涓瀹剁浜у锛锋1涓浣锛村浠ヤ骇涓姝わ濡ㄤ互娉ㄥ杩姣姣绱锛ｄ璇锋濂戒瑕存骇

涓骇浣稿崇

姣姣绱姣绔绉姣绱浜轰郴缁戒瀵瑰朵骇浣涓浣浜х锛娆℃敞灏灏卞芥涓轰棰叉浣浜х锛涓ㄧ堕村澶娆℃敞灏姣姣绱澶锛姹缇涔搴璇ユ敞ギ椋锛涓哄姊惰藉涔戒浜х浣

涓ｈ川浜у浠垮稿崇

ㄤ敞灏姣姣绱藉璇ユ荤ㄧ骇瀹楠绾у姣姣绱娉ㄥ瀹樊澶э璐ㄨ澶锛浠ユ敞灏娉棰娴澶锛变姣姣绱娉ㄥ扮э涓浜茬拷姹楂╂鼎涓椤炬ｈ瀹ㄧ烘戒ㄥ北瀵ㄨ揣杩涓ㄥㄤ藉ㄣ濡娉ㄥ浜杩风浜у锛杞诲锛藉绉し涓搴

缁间杩帮姣姣绱娉ㄥ界舵讳ヨ姣杈瀹浣瀹姣绔涓浜缇ょ锛翠浜涓璐╁濡涓涓х姹缇瑕瀵硅繁璐璐ｇ锛涓搴涓ょ间繁瀹ㄥㄦ浠缁浠浜恒ㄦ敞灏姣姣绱涔蹇椤讳瑙ｇ稿冲荤烘璧璐涔蹇椤绘‘ㄧ浜у板藉璁稿濡姝わ澶х搴颁ㄧ╃

锛浣锛灏村舰绉锛娓ぇ瀛诲棰绉锛诲复搴诲澹

[1] Ascher B,Injection Treatments in Cosmetic Surgery, informa healthcare, 2009

[2] http://en.wikipedia.org/wiki/Botox

[3]Berry MG andStanek JJ, Botulinum neurotoxin A: A review, Journal of Plastic, Reconstructive& Aesthetic Surgery (2012) 65, 1283-91

[4]Shilpa etal., Botulinum toxin: The Midas touch, Journal of Natural Science, Biology andMedicine (2014) 5: 8-14

[5]Grate JW, etal., Revewable surgace fluorescence sandwich immunoassay biosensor for rapidsensitive botulinum toxin detection in an automated fluidic format, Analyst,(2009) 134(5):987-96