浠澶╂涓寮蹇锛ヤ璇朵骇绱灏卞浠ヤ

灏锛寰俊锛yosumn锛璇达璋变濡璺宠锛璺宠涓濡ヤ骇绱锛V3-PNAS锛缇藉藉绉瀛㈤㈡ワ扮绌朵腑锛绉瀛骇绱介杩瑰璁ょヨ绋锛璁╀汉涔瑙锛蹇涓濂斤ヤ锛宸ヤ绱锛ヤ锛惧锛杩涓浼璁╀虹村锝

杩濂界朵唬, 涔朵唬

100骞村存璇寸璇锛ф颁澶╃涓锛浼间绠涓涓涓璐村姝ｄ韩涓拌╄川娲伙绾风炽烘插荤浠朵缁剁惧锛剧渚佃锛涓讳绛绉绯绯浜浠剁舵璁裤

浠娣＄讹舵板涔涓锛涔瑙涓讳姝ｆぇ澶颁汉ㄤ浠ヨ疮涔涔娉渚濡锛涔瀵规板澶瀵逛ョф芥缇ソ锛充究浠浠ラ杩骞寸绂诲ㄤ锛涔舵戒瑙寰繁瀛╁í婧灏界浠浠ラ姣勾骞冲涓楂瀛杩绉瀵硅涔瑙ヨ骞挎瀛ㄤュ父ゆ腑锛寮浜寰澶稿冲绌跺磋叮

涔瑙樊ㄨュ瀛瀹涔涓涔浣瀹涔瑙涓讳锛冲ㄩ㈠澶风绀句娑讹浜轰滑浼╂у版濂芥垮冲拷ラｄ璁ㄤ汉淇℃

淇璇 浜虹藉凤绘涔澶锛姝ｆ杩杩绉涓瀵圭О瀛樊锛浠浠ョ淮俊蹇缂瑙ｇ锛村揩村ソ伴搴ㄩ澧

绌跺锛涔瑙樊杩绉涓瀵圭О瀛瑰跺绉瑕蹇璧婧锛缂轰瑙樊寰戒瀵艰存讹褰惰骞朵崇浠璇ョ茬俊娆轰汉锛

杞诲害ｈㄦ跺板ソ琛ㄧ烘村琛＄瀛妯″搴ｈ冲ㄧ稿茶樊锛浠浠父甯告村版跺涔板蹇界ュソ娑褰卞锛瑙寰浜姣繁冲寸

姝わ淇涔瑙樊浠搴绀句涓涓瑕寰

宠薄浣涓楠涓锛ｄㄤ换￠涓涓涓浣浼瑙濡涓涓や釜涓锛

绗涓

浣璇浼颁骞寸村ュㄤ韬芥фX%锛跺ュㄥㄥぇ锋ラ锛杩涓浠跺ㄥ浣镐技浜虹兢涓骞冲芥фX+20%锛浣ㄨ寰浣澶澶х芥т寰骞寸村

绗涓

浣璇浼颁涓X%锛浣涓浠跺ㄥ浣镐技浜虹兢涓芥фX-20%锛浣ㄨ寰浣澶澶х芥т寰骞寸村

ㄨ涓や釜腑锛浣瑕规淇℃ユ瑰虫锛烘扮ゆ杩跺灏辨涓瀛杩绋

甯告ヨ锛涔瑙樊浣涓猴

浜轰滑浼ㄧ涓绉典杈灏瑰虫锛姣濡锛灏繁虫存颁负X+5%锛锛

ㄧ浜绉典村ぇ骞搴拌村ョ瑙蹇碉姣濡锛灏瑙规存板颁X-15%锛

杩浜轰滑淇″康璋寸骞搴瀵濂藉瀛姣锛绌惰浠浠绮惧伴姣釜浜虹涔瑙樊

捣ワㄨㄤㄥ氨涓ぇ伴荤朵唬锛藉涔瑙樊涓硅甯┿瀛浠寮娲锛涓轰涔瑕绌剁缁藉骇绱ㄥ朵腑浣

纭ヤ锛濂藉锛

骇绱(Oxytocin)锛

绉变涓娉锋杩绁缁斤瀵瑰ぇ榧村绛涓╃躲浜插绀句崇郴瑕浣ㄣ

2005骞达躲蹇琛ㄤ榧诲峰骇绱淇杩浜虹被淇′换绗绡绌朵绌惰浠濮瀵虫敞骇绱ㄧぞ浼璁ょャ缁宸ヤ腑浣ㄣ

榧诲峰骇绱澶ч绌惰〃骇绱澧寮轰浜茬ぞ浼琛涓猴淇杩浜绉绀句浜ゆ2016骞2椹濞绛浜哄琛ㄤ骇绱绀句搴妯″(Social adaptation model)锛哄骇绱杩涓搴绀句澧瑕瀛

澶锛骇绱ㄨ琚ㄤ瀛ょ绀句氦杩浜绀句搴涓兢浣涓村娌荤涓浠ョ绌惰浠寰濂藉锛

ㄤ姘村钩浜轰滑韬锛骇绱绀句搴ㄦ浜鸿寮锛

骇绱瑰茶璁ょュ樊娼ㄥ芥澶澶э

锛灏锛濂芥><浣澶у戒互涓哄濡瑕瀹锛锛

绌惰浠ㄤ涓杩颁俊蹇垫存颁换★ュ瀹楠320涓藉ぇ瀛涓浠榧诲锋ュ骇绱锛Oxytocin锛瀹板锛Placebo锛锛跺ㄧ寰40锛浠ヨ骇绱搴杈惧版浼锛浠诲°

蜂ヨ锛浠浠瑕锛

1. 棣璇浼版ョ涓璐х娲讳浠(姣濡ヨ澶变绛)芥

2. 跺ㄨ寰绀句淇℃棣娆¤琛璇浼般

ㄤ涓瀹楠涓绌跺浜榧诲峰骇绱(intranasal administration of oxytocin)璁╀汉浠村ぇ绋搴板涔浜濂芥苟村版瑰浜繁淇″康锛浜浜轰滑㈠朵俊蹇垫存扮绋搴

涓锛骇绱褰卞涔瑙淇″康褰㈡涓存扮搴锛ㄦ/硅川寰杈楂缇や存撅涔灏辨锛骇绱瀵圭ぞ浼搴涓釜浣璧蜂村ぇ浣锛ョぞ浼搴涓涔瑙樊杈灏浜哄ㄩ蓟峰骇绱ユ浜村涔瑙瀛瑰

骇绱浼褰卞颁瑙蹇锛浠ヤ堪圭锛涓涔娌″崇郴锛浠ョ存缁璁哄锛锛

涓轰颁釜浣杩琛淇″康存版舵寸簿缁璁ょヨ绋锛绌惰璁句涓や釜扮ゆ

瀵硅繁ゆ俊绋搴

瀵瑰棣淇℃绋搴

绌惰浠锛骇绱ㄤ瑙樊涓や褰卞烘瑙蹇垫瑰锛涔褰卞浜俊绋搴浜浜绾у璁ょ(second-order judgment)ㄦ存拌绋锛骞朵骇绱姝ｆ杩褰卞俊绋搴涔瑙樊

涔灏辨锛骇绱浣ㄦ哄跺ㄤ璁╀汉翠俊浠诲ソ娑骞朵跺板ソ娑村俊绋搴姝や骇浜村涔瑙樊

杩浜绌舵涓浠楠璇浜骇绱ㄧぞ浼搴戒浣存绀轰跺ㄦ绛娌荤涓瑕涓村锛抽瑰茶璁ょュ樊锛浼肩骇绱璁告涓癸浠ュ府╄浜绀句戒浜虹兢句瑙宸ユā寮

拌锛灏蹇娼锛蹇涓浣娣瀹浜涓涓骇绱锛惰

杩浜浜у锛浜虹被ㄣ

涓濂濡

PNAS璁烘炬锛 http://www.pnas.org/content/early/2016/07/27/1604285113.abstract

浣锝IDG/楹绉瀛绌堕㈢绀句缁绾ц锛SANP锛瀹楠瀹

村浜绌朵汉绫绘缁宸ュ绀句璁ょョ绁缁╂哄躲充绌跺㈤村绌跺伐浣锛璇疯锛http://brain.bnu.edu.cn/home/yinama/publications.html

棣浜浜蹇澶у锛寰俊锛bnupsychology

绔剧ヨ缁

卞蹇浜哄哄锛杞浇璇疯绯绘绔棣骞冲

Ma, Y., Li, S., Wang, C., Liu, Y., Li, W., Yan, X., Chen, Q., Han, S. (in press). Distinct oxytocin effects on belief updating in response to desirable and undesirable feedback. Proc Natl Acad Sci USA. 2016; published ahead of print August 1, 2016, doi:10.1073/pnas.1604285113

Ma, Y., Shamay-Tsoory, S., Han, S., Zink, C. F. (2016). Oxytocin and social adaptation: Insights from neuroimaging studies of healthy and clinical populations. Trends Cogn Sci, 20: 133-145.